Latisse

 

What is LATISSE® (bimatoprost ophthalmic solution) 0.03%?

LATISSE® solution is a prescription treatment for hypotrichosis used to grow eyelashes, making them longer, thicker and darker.Latisse_Logo

What is hypotrichosis?

Hypotrichosis is another name for having inadequate or not enough eyelashes.

How was LATISSE® discovered?

It’s a story of how one great product led to another. In 2001, Allergan developed a 
medicated eye drop used to treat ocular hypertension. Then, a side effect was 
discovered — patients began growing longer, fuller and darker lashes. This led 
Allergan to study the active ingredient in this other product, and after a clinical trial, 
LATISSE® was born, earning its FDA approval in December 2008.

How does LATISSE® work?

LATISSE® is believed to affect the growth (anagen) phase of the eyelash hair cycle in 
two ways: first, it increases the length of this phase; and second, it increases the 
number of hairs in this growth phase. The exact way it works is unknown.

Is LATISSE® effective?

The LATISSE® clinical study was conducted at 16 sites across the country and 
included 278 participants, featuring women and men of various ages (22 to 78), 
backgrounds and eye colors. Throughout the course of the 16-week treatments, each 
participant was photographed and evaluated at 4-week intervals (week 0 to week 16) 
for differences in their overall lash prominence, including elements of length, thickness 
and fullness. At 16 weeks, the results showed that LATISSE® was effective for 78% of 
those participating, versus 18% for the vehicle group. Vehicle is the same as 
LATISSE®, without its active ingredient.

How soon will I see results?

LATISSE® users may start to see longer lashes at 4 weeks, with full growth at 16 
weeks. The growth is gradual over time.
LATISSE® solution is a once-a-day treatment you apply yourself each evening to the 
base of the upper eyelashes. DO NOT APPLY in your eye or to the lower lid, because 
excess hair growth outside the treatment area may occur. See the full instructions in 
How to Apply, and apply as instructed by your doctor.

Why do the directions say to only apply LATISSE® solution to the base of the 
upper eyelashes?

The clinical studies of LATISSE® were conducted on patients who applied the product 
to the base of their upper lashes only. DO NOT APPLY in your eye or to the lower lid. 
There is the potential for hair growth to occur in areas where LATISSE® solution comes 
in repeated contact with the skin surface. It is important to apply LATISSE® only to the 
skin of the upper eyelid margin at the base of the eyelashes using the accompanying 
sterile applicators, and to carefully blot any excess LATISSE® from the eyelid margin to 
avoid its running onto the cheek or other skin areas.

What if I forget to apply one night? Or a few nights?

If you miss an application, or a few, don’t try to catch up. Just apply the LATISSE® 
treatment the next evening and stay on schedule.

How do I maintain my results?

To achieve the full effect of LATISSE®, you will need to use the product daily for 16 
weeks. After that point, you can talk to your doctor about ongoing use.

What should I do if I wear contact lenses?

Contact lens wearers can use LATISSE®. They need to remove their lenses before 
applying the solution and can reinsert their contacts 15 minutes afterwards.

Yes. In its first year alone, approximately 1.5 million bottles of LATISSE® were 
prescribed.

What are the possible side effects of LATISSE®?

The most common side effects after using LATISSE® solution are an itching sensation 
in the eyes and/or eye redness. This was reported in approximately 4% of patients. 
LATISSE® solution may cause other less common side effects which typically occur on 
the skin close to where LATISSE® is applied, or in the eyes. These include skin 
darkening, eye irritation, dryness of the eyes, and redness of the eyelids. If you 
develop a new ocular condition (e.g., trauma or infection), experience a sudden 
decrease in visual acuity, have ocular surgery, or develop any ocular reactions, 
particularly conjunctivitis and eyelid reactions, you should immediately seek your 
physician’s advice concerning the continued use of LATISSE® solution.

Are there any special warnings associated with LATISSE® use?

>LATISSE® solution is intended for use on the skin of the upper eyelid margins at the 
base of the eyelashes. Refer to the illustration below. DO NOT APPLY to the lower 
eyelid. If you are using other products in the same class for elevated intraocular 
pressure (IOP), or if you have a history of abnormal IOP, you should only use 
LATISSE® under the close supervision of your physician. LATISSE® use may cause 
darkening of the eyelid skin which may be reversible. LATISSE® use may also cause 
increased brown pigmentation of the colored part of the eye which is likely to be 
permanent.  It is possible for hair growth to occur in other areas of your skin that 
LATISSE® frequently touches. Any excess solution outside the upper eyelid margin 
should be blotted with a tissue or other absorbent material to reduce the chance of this 
from happening. It is also possible for a difference in eyelash length, thickness, 
fullness, pigmentation (darkness), number of eyelash hairs, and/or direction of eyelash 
growth to occur between eyes (e.g. results may vary for each eye). These differences, 
should they occur, will usually go away if you stop using LATISSE®.

What should I do if I get LATISSE® into my eye?

LATISSE® solution is an ophthalmic drug product. If any gets into the eye, it is not 
expected to cause harm. The eye does not need to be rinsed.

Who should NOT use LATISSE®?

Do not use LATISSE® solution if you are allergic to one of its ingredients. What are the 
ingredients in LATISSE®? Active ingredient: bimatoprost
Inactive ingredients: benzalkonium chloride; sodium chloride; sodium phosphate, 
dibasic; citric acid; and purified water. Sodium hydroxide and/or hydrochloric acid may 
be added to adjust pH. The pH during its shelf life ranges from 6.8 – 7.8.

What is elevated intraocular pressure (IOP)?

This is a condition where the pressure inside the eye is higher than normal. LATISSE® 
may decrease IOP. So talk to your doctor if you are using IOP-lowering medications. 
Concurrent administration of LATISSE® and certain IOP-lowering medications in ocular 
hypertensive patients should be closely monitored for changes in intraocular pressure.

What should I do if I experience eye redness?

Eye redness may occur immediately after use. Consult your doctor if the redness 
persists or you notice other symptoms as well. If you develop a new eye condition (e.g. 
trauma or infection), experience a sudden decrease in visual acuity, have eye surgery, 
or develop any eye reactions, particularly conjunctivitis and eyelid reactions, you 
should immediately seek your physician’s advice concerning the continued use of
LATISSE®.

What should I do if I experience eye itching?

Eye itching may occur immediately after use. Consult your doctor if the itching persists 
or you notice other symptoms as well. If you develop a new eye condition (e.g. trauma 
or infection), experience a sudden decrease in visual acuity, have eye surgery, or 
develop any eye reactions, particularly conjunctivitis and eyelid reactions, you should 
immediately seek your physician’s advice concerning the continued use of LATISSE®.
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Could LATISSE® cause the color of my eyes to change?

Increased brown iris pigmentation has occurred when the same formulation of 
bimatoprost ophthalmic solution was instilled directly into the eye to treat elevated 
intraocular pressure. Although iris pigmentation was not reported in clinical studies with 
LATISSE®, patients should be advised about the potential for increased brown iris 
pigmentation which is likely permanent.

Is LATISSE® an eye drop?

LATISSE® solution is applied topically, along the skin of the upper eyelashes. It is not 
intended for use in the eyes, but if some solution gets into your eye, you do not need to 
rinse it. See the full instructions in How to Apply, and apply as instructed by your doctor.

If I apply more LATISSE®, will I get faster results?

No. LATISSE® works gradually over the 16-week treatment period. Use of LATISSE® 
more than once a day will not increase the growth of eyelashes. Please follow the 
directions, as instructed by your doctor.

Since LATISSE® is relatively new, should I wait before using it?

LATISSE® received its FDA approval in December 2008, after a team of 16 
experienced doctors from all over the country conducted clinical studies. LATISSE® is 
from Allergan, a specialty pharmaceutical company. Approximately 1.5 million kits of 
LATISSE® have been sold.

Could it darken my eyelids?

Skin hyperpigmention (or skin darkening) is a less common side effect, which typically 
occurs close to where the solution is applied on the skin. This is due to an increase of 
melanin in the skin. The pigmentation is expected to increase as long as bimatoprost is 
administered, but has been reported to be reversible in most patients upon 
discontinuation of bimatoprost.

Can it harm my eyesight?

LATISSE® is an ophthalmic solution. If any solution gets into the eye, it is not expected 
to cause harm. You do not need to rinse your eyes. LATISSE® is not an eye drop. DO 
NOT APPLY in your eye or to the lower lid.

Who besides a specialist can prescribe LATISSE®?

Many different types of doctors can prescribe LATISSE®, including dermatologists, 
plastic surgeons, ophthalmologists, OB/GYNs and primary care doctors. However, not 
all doctors may be familiar with it. To find one who is, use the Find-A-Doctor tool.

How is LATISSE® different from over-the-counter products for lash growth?

LATISSE® is the first and only FDA-approved prescription treatment for inadequate or 
not enough lashes, growing them longer, fuller and darker.

Is LATISSE® a replacement for mascara?

No. LATISSE® does not work in place of mascara. LATISSE® is a solution treatment for 
inadequate or not enough lashes and requires a prescription from a doctor. However, 
mascara can be used on your eyelashes in addition to LATISSE®.

Do I need to refill my LATISSE® prescription every month?

To achieve the full effect of LATISSE® — longer, fuller, darker lashes — you will need 
to use the product daily for 16 weeks. After that point, you should talk to your doctor 
about ongoing use.

What happens if I stop using LATISSE®?

If you stop using LATISSE®, your eyelashes are expected to return to their previous 
appearance over several weeks to months.

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